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AMKD

Professional Resources

Download these additional materials and resources to deepen your knowledge about APOL1 variants and AMKD.

Key Academic Publications

Role of APOL1 Gene in Kidney Disease

Kopp. APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy. J Am Soc Nephrol. 2011 (10 mins)

Genovese. Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science. 2010 (5 mins)

Epidemiology of AMKD

Nadkarni. Worldwide Frequencies of APOL1 Renal Risk Variants. N Engl J Med. 2018 (3 mins)

Chen. APOL1 Risk Variants and Cardiovascular Disease: Results From the AASK (African American Study of Kidney Disease and Hypertension). Arterioscler Thromb Vasc Biol. 2017 (10 mins)

Clinical Presentations of AMKD

Elliott. Clinical and Genetic Characteristics of CKD Patients with High-Risk APOL1 Genotypes. J Am Soc Nephrol. 2023 (10 mins)

Hung. Genetic Inhibition of APOL1 Pore-Forming Function Prevents APOL1-Mediated Kidney Disease. J Am Soc Nephrol. 2023 (10 mins)

Nguyen. APOL1 Genotype, Proteinuria, and the Risk of Kidney Failure: A Secondary Analysis of the AASK (African American Study of Kidney Disease and Hypertension) and CRIC (Chronic Renal Insufficiency Cohort) Studies. Kidney Med. 2022 (5 mins)

Parsa. APOL1 risk variants, race, and progression of chronic kidney disease. N Engl J Med. 2013 (10 mins)

Importance of Genetic Testing in an AMKD Diagnosis

Dahl. The Clinical Utility of Genetic Testing in the Diagnosis and Management of Adults with Chronic Kidney Disease. J Am Soc Nephrol. 2023 (10 mins)

Freedman. Diagnosis, Education, and Care of Patients with APOL1-Associated Nephropathy: A Delphi Consensus and Systematic Review. J Am Soc Neph. 2021 (10 mins)

Friedman. APOL1 Nephropathy: From Genetics to Clinical Applications. Clin J Am Soc Neph. 2021 (10 mins)

Umeukeje. You Are Just Now Telling Us About This? African American Perspectives of Testing for Genetic Susceptibility to Kidney Disease. J Am Soc Nephrol. 2019 (10 mins)

Educational Resources

APOL1 At a Glance Brochure

AMKD at a glance Brochure

Dive into AMKD, the APOL1 gene and African ancestry clinical presentation, and how to diagnose.

AMKD Genetic Testing Postcard

Genetic Testing Postcard

Explore details about no-cost APOL1 genetic testing options available for eligible patients.

Dive Deeper Into APOL1 Testing

Learn about genetic testing options for eligible patients.